abstract：:Two unusual structures were found in the epidermal Langerhans' cells of normal human adult skin: (1) an intramitochondrial crystalline lattice structure composed of numerous electron-dense, fine particles approximately 90 A in diameter, with a lucent spacing of nearly 90 A; (2) bundles of unusual cytoplasmic tubular s...

journal_title：Acta dermato-venereologica

authors： Morohashi M,Hashimoto K

更新日期：1981-01-01 00:00:00

abstract：:5-S-Cysteinyldopa and dopa concentrations in serum were studied by high-performance liquid chromatography (HPLC) in patients with psoriasis treated by 8-methoxypsoralen and UVA light. A marked increase in 5-S-Cysteinyldopa was found after 3 days' treatment, although no increase in pigmentation could yet be observed. T...

journal_title：Acta dermato-venereologica

authors： Hansson C,Rorsman H,Rosengren E,Tegner E

更新日期：1981-01-01 00:00:00

abstract：:We report the clinical variations and the duration of prodromal symptoms in 20 patients with bullous pemphigoid. Nearly two-thirds of the patients had prodromal symptoms. THe duration of the prodromal eruptions was up to 6 weeks if papular and/or urticarial and up to 2 years if eczematous, before the blisters appeared...

journal_title：Acta dermato-venereologica

authors： Asbrink E,Hovmark A

更新日期：1981-01-01 00:00:00

abstract：:This hitherto unknown and dominantly inherited disorder is characterized by vermiculate atrophoderma, milia, hypotrichosis, trichoepitheliomas, basal cell carcinomas and peripheral vasodilation with cyanosis. It has been present in the family reported for at least four generations. The lesions become visible in late c...

journal_title：Acta dermato-venereologica

authors： Michaëlsson G,Olsson E,Westermark P

更新日期：1981-01-01 00:00:00

abstract：:To assess the role of epidermal melanin in a patient with porphyria variegata and vitiligo, the MED was determined in pigmented and vitiliginous skin for wavelengths of 310, 405 and 500 nm. The energy required to elicit erythema by irradiating vitiliginous skin at 310 nm was half that for pigmented skin. For 405 nm th...

journal_title：Acta dermato-venereologica

authors： Westerhof W,Bebelaar D,Cormane RH,Langelaar J,Hup JM

更新日期：1981-01-01 00:00:00

abstract：:The role of cell-mediated immunity in controlling Basal Cell Carcinoma (BCC) growth was studied by measuring the transformation of lymphocytes when challenged in vitro with aqueous extracts of the patients' BCCs and of control skin. Tests were carried out in the presence of autologous and heat-treated plasma. Three pa...

journal_title：Acta dermato-venereologica

authors： Raffle EJ,MacLeod TM,Hutchinson F

更新日期：1981-01-01 00:00:00

abstract：:With fluorescence-histochemical methods (FIF method) pigment-producing cells were investigated in benign and malignant skin lesions. Here, pigment cells appear predominantly dendritic, whilst they are separated from each other by keratinocytes, cells of hair follicles, or cells of sebaceous glands. In lentigo maligna ...

journal_title：Acta dermato-venereologica

authors： Paul E

更新日期：1980-01-01 00:00:00

abstract：:The WR, Kline and VDRL reactions were compared in 496 cases of syphilis. The VDRL was significantly more sensitive than both WR and Kline. ...

journal_title：Acta dermato-venereologica

authors： Berntsson E,Larsson P

更新日期：1980-01-01 00:00:00

abstract：:The proportions of suppressor T cells (TG) and helper T cells (TM) were determined in 5 patients with Mycosis fungoides (MF), 4 patients with parapsoriasis en plaques/poikiloderma atrophicans vasculare and 3 patients with generalized chronic dermatitis. All the MF patients showed increased proportions of suppressor T ...

journal_title：Acta dermato-venereologica

authors： Wassermann J,Biberfeld G,Baral E,Blomgren H,Thyresson N,Brehmer-Andersson E

更新日期：1980-01-01 00:00:00

abstract：:Irritation and staining by dithranol and some 10-meso-substituted acyl analogues was studied with the chamber-testing technique in a series of 50 psoriasis patients. The test concentrations for dithranol, 10-acetyldithranol, 10-propionyldithranol and 10-butyryldithranol were 0.05 and 0.5%, for 10-valeryldithranol 5% a...

journal_title：Acta dermato-venereologica

authors： Mustakallio KK

更新日期：1980-01-01 00:00:00

abstract：:Tissue from buccal and labial mucosal lesions of discoid lupus erythematosus (DLE) was studied in the electron microscope. The material comprised 10 patients, 7 of whom presented skin lesions as well. The epithelium showed a change in differentiation pattern from nonkeratinizing to keratinizing epithelium. Civatte bod...

journal_title：Acta dermato-venereologica

authors： Schiødt M,Andersen L

更新日期：1980-01-01 00:00:00

abstract：:Zinc deficiency was produced in rats by feeding them a diet containing 0.5 mg zinc per kg. After 2 weeks the zinc-deficient rats showed markedly stunted growth as compared with control rats receiving an identical diet supplemented with 50 mg zinc per kg. After about 3 weeks all rats in the zinc-deficient group develop...

journal_title：Acta dermato-venereologica

authors： Weismann K,Christophersen J,Kobayasi T

更新日期：1980-01-01 00:00:00

abstract：:Lymphocytes in chronic lymphocytic leukaemia and in other malignant lymphomas exhibit an extreme sensitivity to colchicine and are cytolysed in vitro by 10(-6) M colchicine. This characteristic can be quantified with the colchicine sensitivity index which is used for diagnostic purposes. We have demonstrated that lymp...

journal_title：Acta dermato-venereologica

authors： Sterry W,Steigleder GK,Nikolai B

更新日期：1980-01-01 00:00:00

abstract：:Oxidation of 5-S-cysteinyldopa by mushroom tyrosinase was studied by measuring 5-S-cysteinyldopa consumption with HPLC. 5-S-cysteinyldopa was found to be a substrate for tyrosinase, but our results suggests that a self-catalysed oxidation induced by enzymatically formed 5-S-cysteinyl dopaquinone also takes place. Dopa...

journal_title：Acta dermato-venereologica

authors： Hansson C,Rorsman H,Rosengren E

更新日期：1980-01-01 00:00:00

abstract：:The nail--patella syndrome is a rare, inheritable disease of the connective tissue in which multiple osseous abnormalities are associated with dysplasia of the nails. Renal dysfunction is found in 25--42% of cases and varies from asymptomatic proteinuria to renal failure. This paper describes a patient with nail--pate...

journal_title：Acta dermato-venereologica

authors： Verdich J

更新日期：1980-01-01 00:00:00

abstract：:Dermal cells maintained in cultured human skin explants for up to 10 weeks were studied by electron microscopy. Common findings in the cell organelles were: 1) altered nuclear shapes and numerous nuclear bodies; 2) reduced rough endoplasmic reticulum; 3) a prominent Golgi complex; and 4) an increasing number of free r...

journal_title：Acta dermato-venereologica

authors： Hentzer B,Kobayasi T

更新日期：1980-01-01 00:00:00

abstract：:Human leukocytes and fibroblasts were cultured in medium containing 3H-8-methoxypsoralen (10(-6) M and 3.3 X 10(-6) M). At different stages during the culturing period the cells were exposed to ultraviolet light (1, 2, and 10 J/cm2). After the culture period the slides for chromosome analysis and smears of the cells w...

journal_title：Acta dermato-venereologica

authors： Wulf HC,Niebuhr E

更新日期：1980-01-01 00:00:00

abstract：:The delayed-type immune reactivities of 39 patients suffering from moderate to severe papulopustular or nodulo-cystic forms of Acne vulgaris were compared with healthy acne-free controls. In vivo reactivity was assessed by skin testing with four common recall antigens. In vitro the afferent arm of the immune system wa...

journal_title：Acta dermato-venereologica

authors： Ashorn R,Uotila A,Kuokkanen K,Räsänen L,Karhumäki E,Krohn K

更新日期：1980-01-01 00:00:00

abstract：:A 45-year-old woman with solar urticaria is described. She was found to have: (a) increase of skin mast cells; (b) a good therapeutic response to hydroxyzine hydrochloride; (c) frequent peptic ulcers of the stomach; (d) antinuclear IgM antibodies in a titre of 1 : 1 000; (e) cold urticaria and dermographism; (f) anamn...

journal_title：Acta dermato-venereologica

authors： Rantanen T,Suhonen R

更新日期：1980-01-01 00:00:00

abstract：:The skin relief influences the exterior aspect of the skin which is very sensitive to aging. It could also be related to the mechanical properties and structure of both dermis and stratum corneum. Consequently, quantitative measurement of the skin surface roughness would seem most useful, as it would permit a quantifi...

journal_title：Acta dermato-venereologica

authors： Makki S,Barbenel JC,Agache P

更新日期：1979-01-01 00:00:00

abstract：:Determinations of the urinary excretion of 5-S-cysteinyldopa were performed in 571 patients previously treated by surgery for melanoma or melanoma metastasis. 90% of the 161 patients with metastases showed values exceeding 0.15 mg/24 h, and 9% of the 410 patients without metastases had such values. The increase in 5-S...

journal_title：Acta dermato-venereologica

authors： Agrup G,Agrup P,Andersson T,Hafström L,Hansson C,Jacobsson S,Jönsson PE,Rorsman H,Rosengren AM,Rosengren E

更新日期：1979-01-01 00:00:00

abstract：:Blood levels of serotonin (5-HT) and urinary excretion of 5-hydroxyindole-acetic acid (5-HIAA), tryptamine (T), and indole-acetic acid (IAA) were determined in 39 cases of systemic scleroderma and in 7 cases of very severe cutaneous scleroderma. The T/IAA ratio was normal and serotonin elevated in mild and rather seve...

journal_title：Acta dermato-venereologica

authors： Stachów A,Jabłońska S,Skiendzielewska A

更新日期：1979-01-01 00:00:00

abstract：:ESR spectra of synthetic melanins formed from dopa and from 5-S-cysteinyldopa and of melanins isolated from human melanomas were studied. Alkali-soluble melanin synthesized from cysteinyldopa showed a signal similar to that of insoluble melanin synthesized from dopa, but also a simple fine structure. Trichochromes C a...

journal_title：Acta dermato-venereologica

authors： Hansson C,Agrup G,Rorsman H,Rosengren AM,Rosengren E

更新日期：1979-01-01 00:00:00

abstract：:The Scandinavian Mycosis Fungoides Study Group has treated 21 patients with mycosis fungoides in plaque stages with topical, whole-body application of nitrogen mustard, 20 mg in 40 ml water per square metre. Ten patients were treated after previous attempts at intravenous tolerance induction ad modum van Scott & Kalma...

journal_title：Acta dermato-venereologica

authors： Molin L,Thomsen K,Volden G

更新日期：1979-01-01 00:00:00

abstract：:Urinary excretion of proline and hydroxyproline was studied in five groups of subjects, viz. controls, pituitary dwarfs, familial dwarfs, patients with fibrodysplasia ossificans progressive and patients with generalized scleroderma. The ratio Pro/Hyp in the urinary fraction precipitated with 5 parts of acetone (1 + 5 ...

journal_title：Acta dermato-venereologica

authors： Blumenkrantz N,Howitz P,Asboe-Hansen G

更新日期：1979-01-01 00:00:00

abstract：:Epipodophyllotoxin (VP-16-213) was administered to 9 patients with mycosis fungoides in various stages, most of them in the advanced tumour stage. In 4 of the patients VP-16 was combined with cyclophosphamide. VP-16 alone or in combination with cyclophosphamide was capable of inducing remission initially in all cases,...

journal_title：Acta dermato-venereologica

authors： Molin L,Thomsen K,Volden G,Bergqvist-Karlsson A,Hallberg O,Hellbe L

更新日期：1979-01-01 00:00:00

abstract：:Cell-mediated immunity in patients with verified dermatophytosis was investigated by means of skin test and lymphocyte stimulation test (LST) using purified trichophytin, prepared by the ethylene glycol method, and commercially available trichophytin. The purified trichophytin seemed to be more specific and sensitive ...

journal_title：Acta dermato-venereologica

authors： Kaaman T,Petrini B,Wasserman J

更新日期：1979-01-01 00:00:00

abstract：:In two Arab brothers presenting the characteristic clinical picture of epidermodysplasia verruciformis (EV), histological examination revealed large clear cells in the granular layer and uppermost part of the prickle cell layer of the epidermis. The report of this histological picture in two cases by other authors in ...

journal_title：Acta dermato-venereologica

authors： Feuerman EJ,Sandbank M,David M

更新日期：1979-01-01 00:00:00

abstract：:A report is given of the successful treatment with transfer factor as an additional therapeutic agent of a patient in the tumour stage of mycosis fungoides who had not responded to conventional treatment with nitrogen mustard, methotrexate, or grenz rays alone. Besides twelve injections of transfer factor, the patient...

journal_title：Acta dermato-venereologica

authors： Zachariae H,Grunnet E,Thestrup-Pedersen K

更新日期：1979-01-01 00:00:00

abstract：:Fifteen patients with nodular prurigo were treated with a trioxsalen bath (50 mg/150 l of water) and UVA given in an ordinary PUVA cabin. Good results were observed in 8 and moderate in 7 patients in the initial phase. The result was good or excellent in 13 of the 15 patients during maintenance treatment. The good res...

journal_title：Acta dermato-venereologica

authors： Väätäinen N,Hannuksela M,Karvonen J

更新日期：1979-01-01 00:00:00

abstract：:Sweat from 8 'rusters' and 8 control persons was examined for its sodium concentration. Sweating was induced by iontophoresis of pilocarpine on the distal forearm. In no case did the concentrations exceed the normal upper limit for this procedure, and no difference was found between the two groups. In this way the stu...

journal_title：Acta dermato-venereologica

authors： Jensen O

更新日期：1979-01-01 00:00:00

abstract：:Skin perfusion pressure in fingers in 6 normal persons and 12 patients suffering from generalized scleroderma was estimated as the minimum external counterpressure required to stop 133Xenon wash-out. The isotope was introduced atraumatically into the skin, and local counter-pressure was exerted by a miniature blood pr...

journal_title：Acta dermato-venereologica

authors： Kristensen JK

更新日期：1978-01-01 00:00:00

abstract：:Indirect immunofluorescence (IF) studies were performed on skin from a variety of vertebrate specimens and IgG fractions from pemphigoid and pemphigus sera. Pemphigoid antigen was present in fish, amphibian, reptilian, avian and mammalian skin, whereas pemphigus antigen was observed in avian and mammalian skin only. ...

journal_title：Acta dermato-venereologica

authors： Diaz LA,Weiss HJ,Calvanico NJ

更新日期：1978-01-01 00:00:00

abstract：:Lymphocytes from 8 patients with contact dermatitis and a positive nickel patch test, 7 patients with contact dermatitis due to other factors and with a negative nickel patch test, and 9 other subjects, 7 of whom suffered from other dermatological disorders, were tested with the lymphocyte transformation test (LTT), u...

journal_title：Acta dermato-venereologica

authors： Svejgaard E,Morling N,Svejgaard A,Veien NK

更新日期：1978-01-01 00:00:00

abstract：:Three-day-old rat skins were treated either by the freezing--thawing method or by the tetraphenylboron technique. After the former procedure, keratohyalin granules were solubilized, leaving empty spaces with an electron-dense or less dense rim. Particles roughly 200 A in diameter, which were either electron-dense or l...

journal_title：Acta dermato-venereologica

authors： Tezuka T,Hirai R

更新日期：1978-01-01 00:00:00

abstract：:Patients with palpebral cellulitis may turn in the first place to a skin clinic. The clinical picture and the course of disease are illustrated here by four case histories. The importance of differentiating between collateral orbital edema, palpebral cellulitis and orbital cellulitis is stressed. ...

journal_title：Acta dermato-venereologica

authors： Roed-Petersen J,Larsen HW

更新日期：1978-01-01 00:00:00

abstract：:In order to study the development of atrophic gastritis, gastric secretory function was examined by a standard pentagastrin test 24 to 78 months after a previous examination (Ex I). The study included 12 patients with dermatitis herpetiformis (DH), 6 patients with functional signs of atrophic gastritis previously, and...

journal_title：Acta dermato-venereologica

authors： Stockbrügger R,Kastrup W,Lundqvist G,Mobacken H

更新日期：1978-01-01 00:00:00

abstract：:A 73-year-old woman with rheumatoid arthritis was treated with Levamisole, 150 mg per day, on 2 days a week. Her arthritis improved, but she developed a severely itching rash, and the treatment was stopped after 6 months. Penicillamine was subsequently given and tolerated without skin complications. 15 months after re...

journal_title：Acta dermato-venereologica

authors： Secher L,Permin H,Skov PS,Ullman S,Halberg P

更新日期：1978-01-01 00:00:00

abstract：:Low molecular weight oligomers of an epoxy resin of bisphenol A diglycidyl ether type were isolated by gel permeation chromatography. The sensitizing capacity of these oligomers was assessed with the "guinea pig maximization test". The oligomer with the molecular weight of 340 sensitized 80% to 100% of the animals, bu...

journal_title：Acta dermato-venereologica

authors： Thorgeirsson A,Fregert S,Ramnäs O

更新日期：1978-01-01 00:00:00

abstract：:The skin absorption of clioquinol and chloroquinaldol in ointment or cream base was studied in fourteen patients with widespread dermatoses. A serum concentration in the range of 0.3--1.3 microgram/ml using clioquinol and 0.05--0.1 microgram/ml with chloroquinaldol was reached by the second day and persisted throughou...

journal_title：Acta dermato-venereologica

authors： Fischer T,Fagerlund C,Hartvig P

更新日期：1978-01-01 00:00:00